Our Products
We focus on developing technologies targeting unmet medical challenges such as oncology and infectious diseases by means of nanotechnology
ON MARKET
Paclitaxel protein boud particles; Nab-Placlitaxel
Nanoparticle albumin-bound Paclitaxel or Nab-Paclitaxel is an injectable formulation used as standard of care for breast, lung and pancreatic cancer. Formulation of Paclitaxel as albumin nanoparticles improves the toxicity profile (when compared with previous formulations) allowing for higher doses during treatment. Paclitaxel mode of action prevents normal breakdown of cancerous cells microtubules during division.
Indicated for the treatment of metastatic breast cancer in adult patients who have failed first-line treatment for metastatic disease
Nanoparticles, Lyoph. Inject.
Abraxane™ (Celgene)
ON MARKET
Octreotide depot
Octreotide is a synthetic peptide that mimics natural somatostatin although with a more potent inhibitor activity towards growth hormone, glucagon, and insulin.
Octreotide is used for the treatment of growth hormone producing tumors (acromegaly and gigantism), when surgery is contraindicated, pituitary tumors that secrete thyroid stimulating hormone (thyrotropinoma), diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide-secreting tumors.
PLGA microspheres, Lyoph. Inject.
Sandostatin™Lar Depot (Novartis)
ON MARKET
Doxonax
Pegylated Liposomal Doxorubicin is a polyethylene glycol coated liposome-encapsulated form of doxorubicin used to treat cancer. It was the first nanomedicine approved by FDA. This formulation was developed to overcome clearance of previous liposomal formulations (which addressed doxorubicin traditional formulation´s toxic side effects). Doxorubicin is actively loaded using a transmembrane ionic gradient.
Used to treat breast cancer, ovarian cancer, myeloma, and HIV-related Kaposi's sarcoma. Also used as second line treatment for other types of cancer.
Pegylated liposome, Injectable solution.
Caelyx™ (Schering Plough)
ON MARKET
Amphotericin B Liposome
Liposomal Amphotericin B is comprised of Amphotericin B drug molecules intercalated in single bilipid layer liposomes. It is formulated as a sterile, non-pyrogenic lyophilized powder for reconstitution for intravenous infusion.
Used to treat fungal infections such as cryptococcal meningitis and visceral leishmaniasis
Liposomes, Lyoph. Inject
Ambisome™ (Gilead)
ON MARKET
Leuprolide depot 1 and 3 months
Leuprolide is a synthetic peptide analog of the naturally occurring gonadotrophin releasing hormone with increased activity. This injectable formulation relies on polymer microspheres to improve release profile, reducing application frequency to once every 1 or 3 months instead of daily applications.
Used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis or uterine fibroids
PLGA microspheres, Lyoph. Inject
Lupron™ (Abbott)
Pipeline
ON MARKET
Paclitaxel protein boud particles; Nab-Placlitaxel
Nanoparticle albumin-bound Paclitaxel or Nab-Paclitaxel is an injectable formulation used as standard of care for breast, lung and pancreatic cancer. Formulation of Paclitaxel as albumin nanoparticles improves the toxicity profile (when compared with previous formulations) allowing for higher doses during treatment. Paclitaxel mode of action prevents normal breakdown of cancerous cells microtubules during division.
Indicated for the treatment of metastatic breast cancer in adult patients who have failed first-line treatment for metastatic disease
Nanoparticles, Lyoph. Inject.
Abraxane™ (Celgene)
ON MARKET
Octreotide depot
Octreotide is a synthetic peptide that mimics natural somatostatin although with a more potent inhibitor activity towards growth hormone, glucagon, and insulin.
Octreotide is used for the treatment of growth hormone producing tumors (acromegaly and gigantism), when surgery is contraindicated, pituitary tumors that secrete thyroid stimulating hormone (thyrotropinoma), diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide-secreting tumors.
PLGA microspheres, Lyoph. Inject.
Sandostatin™Lar Depot (Novartis)
ON MARKET
Doxonax
Pegylated Liposomal Doxorubicin is a polyethylene glycol coated liposome-encapsulated form of doxorubicin used to treat cancer. It was the first nanomedicine approved by FDA. This formulation was developed to overcome clearance of previous liposomal formulations (which addressed doxorubicin traditional formulation´s toxic side effects). Doxorubicin is actively loaded using a transmembrane ionic gradient.
Used to treat breast cancer, ovarian cancer, myeloma, and HIV-related Kaposi's sarcoma. Also used as second line treatment for other types of cancer.
Pegylated liposome, Injectable solution.
Caelyx™ (Schering Plough)
ON MARKET
Amphotericin B Liposome
Liposomal Amphotericin B is comprised of Amphotericin B drug molecules intercalated in single bilipid layer liposomes. It is formulated as a sterile, non-pyrogenic lyophilized powder for reconstitution for intravenous infusion.
Used to treat fungal infections such as cryptococcal meningitis and visceral leishmaniasis
Liposomes, Lyoph. Inject
Ambisome™ (Gilead)
ON MARKET
Leuprolide depot 1 and 3 months
Leuprolide is a synthetic peptide analog of the naturally occurring gonadotrophin releasing hormone with increased activity. This injectable formulation relies on polymer microspheres to improve release profile, reducing application frequency to once every 1 or 3 months instead of daily applications.
Used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis or uterine fibroids
PLGA microspheres, Lyoph. Inject
Lupron™ (Abbott)
Nanomedicine
Nanox’s drug carriers enhance the in-vivo efficiency of many drugs, especially anti-cancer drugs which are passively targeted to tumor through enhanced permeability and retention effect, making them ideally suited for the delivery of chemotherapeutics. Nanox portfolio includes many nanoparticle delivery systems developed for cancer therapy, including organic and inorganic active principles.